Pongo and Missis had a lovely life. With their human owners, the Dearlys, to look after them, they lived in a comfortable home in London with their 15 adorable Dalmatian puppies, loved and admired by all. Especially the Dearlys' neighbor Cruella de Vil, a fur-fancying fashion plate with designs on the Dalmatians' spotted coats! So, when the puppies are stolen from the Dearly home, and even Scotland Yard is unable to find them, Pongo and Missis know they must take matters into their own paws